Selected publications
- Kjølle S, Presti M, de Pina Roque J, Bisgaard LH, Ramos DB, Zornhagen KW, Yde CW, Schmidt AY, Verdys P, Højgaard M, Lassen U, Svane IM, Rohrberg KS, Donia M, Erler JT. Immune Cell Modulation of Patient-Matched Organoid Drug Response in Precision Cancer Medicine Platform. Cells. 2026;15(3):259.
- Leitão-Castro J, Lopresti AM, Zornhagen KW, Albrechtsen R, Camacho-Roda J, Ravn MB, Martinez AG, Perez LA, Santoni-Rugiu E, Højgaard M, Rohrberg KS, Lassen U, Erler JT. Histological fidelity and microenvironmental kinome signatures of metastatic patient-derived organoids. Front Bioeng Biotechnol. 2026;14:1735980.
- Oria VO, Castro JL, de Pina Roque J, Martinez AG, Jørgensen FI, Lukassen MV, Rib L, Høg MKG, Mygind KJ, Erler JT. Crosstalk between tumor endothelial cells and cancer cells is important for metastasis initiation. Cell Commun Signal. 2025;23(1):443.
- Xia T, Zornhagen KW, Miinalainen I, Abramovitz L, Madsen CD, Nicolau M, Mayorca-Guiliani AE, Erez N, Erler JT. Loss of nidogen-1 causes lung basement membrane defects and increased metastasis. Front Immunol. 2025;16:1598547.
- Stagaard R, Jensen A, Schauer T, Bay ML, Tavanez ARA, Wielsøe S, Peletier M, Strøbech JE, Oria VO, Zornhagen KW, Albrechtsen R, Christensen JF, Erler JT. Exercise boost after surgery improves survival in model of metastatic breast cancer. Front Immunol. 2025;16:1533798.
- Emerson MJ, Willacy O, Madsen CD, Reuten R, Brøchner CB, Lund TK, Dahl AB, Jensen THL, Erler JT, Mayorca-Guilliani AE. Machine learning identifies remodeling patterns in human lung extracellular matrix. Acta Biomater. 2025;195:94–103.
- Perryman L, Høye AM, Cox TR, Baker AM, Strøbech J, Leonte L, Singh LB, Popov S, Lorentzen LG, Reuten R, Poulsen HS, Davies MJ, Jones C, Erler JT. Cleavage of the vascular matrix attracts glioblastoma cells to infiltrate the brain parenchyma. bioRxiv. 2024.
- Rafaeva M, Jensen ARD, Horton ER, Zornhagen KW, Strøbech JE, Fleischhauer L, Mayorca-Guiliani AE, Nielsen SR, Grønseth DS, Kuś F, Schoof EM, Arnes L, Koch M, Clausen-Schaumann H, Izzi V, Reuten R, Erler JT. Fibroblast-derived matrix models desmoplastic properties and forms a prognostic signature in cancer progression. Front Immunol. 2023;14:1154528.
- Strøbech JE, Giuriatti P, Stagaard R, De Sepulveda P, Nielsen SR, Erler JT. FES null mice demonstrate a reduction in neutrophil dependent pancreatic cancer metastatic burden. Front Oncol. 2023;13:1096499.
- Rafaeva M, Horton ER, Jensen ARD, Madsen CD, Reuten R, Willacy O, Brøchner CB, Jensen TH, Zornhagen KW, Crespo M, Grønseth DS, Nielsen SR, Idorn M, Straten PT, Rohrberg K, Spanggaard I, Højgaard M, Lassen U, Erler JT, Mayorca-Guiliani AE. Modeling Metastatic Colonization in a Decellularized Organ Scaffold-Based Perfusion Bioreactor. Adv Healthc Mater. 2022;11(1):e2100684.
- Reuten R, Zendehroud S, Nicolau M, Fleischhauer L, Laitala A, Kiderlen S, Nikodemus D, Wullkopf L, Nielsen SR, McNeilly S, Prein C, Rafaeva M, Schoof EM, Furtwängler B, Porse BT, Kim H, Won KJ, Sudhop S, Zornhagen KW, Suhr F, Maniati E, Pearce OMT, Koch M, Oddershede LB, Van Agtmael T, Madsen CD, Mayorca-Guiliani AE, Bloch W, Netz RR, Clausen-Schaumann H, Erler JT. Basement membrane stiffness determines metastases formation. Nat Mater. 2021;20(6):892–903.
- Nielsen SR, Strøbech JE, Horton ER, Jackstadt R, Laitala A, Bravo MC, Maltese G, Jensen ARD, Reuten R, Rafaeva M, Karim SA, Hwang CI, Arnes L, Tuveson DA, Sansom OJ, Morton JP, Erler JT. Suppression of tumor-associated neutrophils by lorlatinib attenuates pancreatic cancer growth and improves treatment with immune checkpoint blockade. Nat Commun. 2021;12(1):3414.
- Jensen ARD, Horton ER, Blicher LH, Pietras EJ, Steinhauer C, Reuten R, Schoof EM, Erler JT. Organ-Specific, Fibroblast-Derived Matrix as a Tool for Studying Breast Cancer Metastasis. Cancers (Basel). 2021;13(13):3331.
- Mayorca-Guiliani AE, Rafaeva M, Willacy O, Madsen CD, Reuten R, Erler JT. Decellularization of the Murine Cardiopulmonary Complex. J Vis Exp. 2021;(171).
- Venning FA, Zornhagen KW, Wullkopf L, Sjölund J, Rodriguez-Cupello C, Kjellman P, Morsing M, Hajkarim MC, Won KJ, Erler JT, Madsen CD. Deciphering the temporal heterogeneity of cancer-associated fibroblast subpopulations in breast cancer. J Exp Clin Cancer Res. 2021;40(1):175.
All publications
2026
- Kjølle S, Presti M, de Pina Roque J, Bisgaard LH, Ramos DB, Zornhagen KW, Yde CW, Schmidt AY, Verdys P, Højgaard M, Lassen U, Svane IM, Rohrberg KS, Donia M, Erler JT. Immune Cell Modulation of Patient-Matched Organoid Drug Response in Precision Cancer Medicine Platform. Cells. 2026;15(3):259.
- Leitão-Castro J, Lopresti AM, Zornhagen KW, Albrechtsen R, Camacho-Roda J, Ravn MB, Martinez AG, Perez LA, Santoni-Rugiu E, Højgaard M, Rohrberg KS, Lassen U, Erler JT. Histological fidelity and microenvironmental kinome signatures of metastatic patient-derived organoids. Front Bioeng Biotechnol. 2026;14:1735980.
2025
- Oria VO, Castro JL, de Pina Roque J, Martinez AG, Jørgensen FI, Lukassen MV, Rib L, Høg MKG, Mygind KJ, Erler JT. Crosstalk between tumor endothelial cells and cancer cells is important for metastasis initiation. Cell Commun Signal. 2025;23(1):443.
- Xia T, Zornhagen KW, Miinalainen I, Abramovitz L, Madsen CD, Nicolau M, Mayorca-Guiliani AE, Erez N, Erler JT. Loss of nidogen-1 causes lung basement membrane defects and increased metastasis. Front Immunol. 2025;16:1598547.
- Stagaard R, Jensen A, Schauer T, Bay ML, Tavanez ARA, Wielsøe S, Peletier M, Strøbech JE, Oria VO, Zornhagen KW, Albrechtsen R, Christensen JF, Erler JT. Exercise boost after surgery improves survival in model of metastatic breast cancer. Front Immunol. 2025;16:1533798.
- Emerson MJ, Willacy O, Madsen CD, Reuten R, Brøchner CB, Lund TK, Dahl AB, Jensen THL, Erler JT, Mayorca-Guilliani AE. Machine learning identifies remodeling patterns in human lung extracellular matrix. Acta Biomater. 2025;195:94–103.
2024
- Perryman L, Høye AM, Cox TR, Baker AM, Strøbech J, Leonte L, Singh LB, Popov S, Lorentzen LG, Reuten R, Poulsen HS, Davies MJ, Jones C, Erler JT. Cleavage of the vascular matrix attracts glioblastoma cells to infiltrate the brain parenchyma. bioRxiv. 2024.
2023
- Rafaeva M, Jensen ARD, Horton ER, Zornhagen KW, Strøbech JE, Fleischhauer L, Mayorca-Guiliani AE, Nielsen SR, Grønseth DS, Kuś F, Schoof EM, Arnes L, Koch M, Clausen-Schaumann H, Izzi V, Reuten R, Erler JT. Fibroblast-derived matrix models desmoplastic properties and forms a prognostic signature in cancer progression. Front Immunol. 2023;14:1154528.
- Strøbech JE, Giuriatti P, Stagaard R, De Sepulveda P, Nielsen SR, Erler JT. FES null mice demonstrate a reduction in neutrophil dependent pancreatic cancer metastatic burden. Front Oncol. 2023;13:1096499.
2022
- Rafaeva M, Horton ER, Jensen ARD, Madsen CD, Reuten R, Willacy O, Brøchner CB, Jensen TH, Zornhagen KW, Crespo M, Grønseth DS, Nielsen SR, Idorn M, Straten PT, Rohrberg K, Spanggaard I, Højgaard M, Lassen U, Erler JT, Mayorca-Guiliani AE. Modeling Metastatic Colonization in a Decellularized Organ Scaffold-Based Perfusion Bioreactor. Adv Healthc Mater. 2022;11(1):e2100684.
2021
- Reuten R, Zendehroud S, Nicolau M, Fleischhauer L, Laitala A, Kiderlen S, Nikodemus D, Wullkopf L, Nielsen SR, McNeilly S, Prein C, Rafaeva M, Schoof EM, Furtwängler B, Porse BT, Kim H, Won KJ, Sudhop S, Zornhagen KW, Suhr F, Maniati E, Pearce OMT, Koch M, Oddershede LB, Van Agtmael T, Madsen CD, Mayorca-Guiliani AE, Bloch W, Netz RR, Clausen-Schaumann H, Erler JT. Basement membrane stiffness determines metastases formation. Nat Mater. 2021;20(6):892–903.
- Nielsen SR, Strøbech JE, Horton ER, Jackstadt R, Laitala A, Bravo MC, Maltese G, Jensen ARD, Reuten R, Rafaeva M, Karim SA, Hwang CI, Arnes L, Tuveson DA, Sansom OJ, Morton JP, Erler JT. Suppression of tumor-associated neutrophils by lorlatinib attenuates pancreatic cancer growth and improves treatment with immune checkpoint blockade. Nat Commun. 2021;12(1):3414.
- Jensen ARD, Horton ER, Blicher LH, Pietras EJ, Steinhauer C, Reuten R, Schoof EM, Erler JT. Organ-Specific, Fibroblast-Derived Matrix as a Tool for Studying Breast Cancer Metastasis. Cancers (Basel). 2021;13(13):3331.
- Mayorca-Guiliani AE, Rafaeva M, Willacy O, Madsen CD, Reuten R, Erler JT. Decellularization of the Murine Cardiopulmonary Complex. J Vis Exp. 2021;(171).
- Venning FA, Zornhagen KW, Wullkopf L, Sjölund J, Rodriguez-Cupello C, Kjellman P, Morsing M, Hajkarim MC, Won KJ, Erler JT, Madsen CD. Deciphering the temporal heterogeneity of cancer-associated fibroblast subpopulations in breast cancer. J Exp Clin Cancer Res. 2021;40(1):175.
- Mehlen P, Fattet L. Netrin-4 regulates stiffness and metastasis (News & Views). Nat Mater. 2021;20:722–723.
2020
- Rafaeva M, Erler JT. Framing cancer progression: influence of the organ- and tissue-specific matrisome. FEBS J. 2020.
2019
- Mayorca-Guiliani AE, Willacy O, Madsen CD, Rafaeva M, Heumüller SE, Bock F, Sengle G, Koch M, Imhof T, Zaucke F, Wagener R, Sasaki T, Erler JT, Reuten R. Decellularization and antibody staining of mouse tissues to map native extracellular matrix structures in 3D. Nat Protoc. 2019.
- Blache U, Horton ER, Xia T, Schoof EM, Blicher LH, Schönenberger A, Snedeker JG, Martin I, Erler JT, Ehrbar M. Mesenchymal stromal cell activation by breast cancer secretomes in bioengineered 3D microenvironments. Life Sci Alliance. 2019.
- Amendola PG, Reuten R, Erler JT. Interplay between LOX enzymes and integrins in the tumor microenvironment. Cancers (Basel). 2019;11(5):729.
2018
- Wullkopf L, West AV, Leijnse N, Cox TR, Madsen CD, Oddershede LB, Erler JT. Cancer cell ability to mechanically adjust to extracellular matrix stiffness correlates with their invasive potential. Mol Biol Cell. 2018.
- Høye AM, Tolstrup SD, Horton ER, Nicolau M, Frost H, Woo JH, Mauldin JP, Frankel AE, Cox TR, Erler JT. Tumor endothelial marker 8 promotes cancer progression and metastasis. Oncotarget. 2018;9(53):30173–30188.
- Blache U, Vallmajo-Martin Q, Horton ER, Guerrero J, Djonov V, Scherberich A, Erler JT, Martin I, Snedeker JG, Milleret V, Ehrbar M. Notch-inducing hydrogels reveal a perivascular switch of mesenchymal stem cell fate. EMBO Rep. 2018;19(8):e45964.
- Christensen A, West AV, Wullkopf L, Erler JT, Oddershede LB, Mathiesen J. Friction-limited cell motility in confluent monolayer tissue. Phys Biol. 2018.
- Laitala A, Erler JT. Hypoxic signalling in tumour stroma. Front Oncol. 2018;8:189.
- Xia T, Horton ER, Salcini AE, Pocock R, Cox TR, Erler JT. Proteomic characterisation of Caenorhabditis elegans larval development. Proteomics. 2018;18(2).
2017
- Mayorca-Guiliani AE, Madsen CD, Cox TR, Horton ER, Venning FA, Erler JT. ISDoT: in situ decellularization of tissues for high-resolution imaging and proteomic analysis of native extracellular matrix. Nat Med. 2017;23(7):890–898.
- Peinado H, Zhang H, Matei IR, Costa-Silva B, Hoshino A, Rodrigues G, Psaila B, Kaplan RN, Bromberg JF, Kang Y, Bissell MJ, Cox TR, Giaccia AJ, Erler JT, Hiratsuka S, Ghajar CM, Lyden D. Pre-metastatic niches: organ-specific homes for metastases. Nat Rev Cancer. 2017;17(5):302–317.
- Koplev S, Longden J, Ferkinghoff-Borg J, Blicher Bjerregård M, Cox TR, Erler JT, Pedersen JT, Voellmy F, Sommer MOA, Linding R. Dynamic rearrangement of cell states detected by systematic screening of sequential anticancer treatments. Cell Rep. 2017;20(12):2784–2791.
- Chang J, Lucas MC, Leonte LE, Garcia-Montolio M, Singh LB, Findlay AD, Deodhar M, Foot JS, Jarolimek W, Timpson P, Erler JT, Cox TR. Pre-clinical evaluation of small molecule LOXL2 inhibitors in breast cancer. Oncotarget. 2017;8(16):26066–26078.
- West AV, Wullkopf L, Christensen A, Leijnse N, Tarp JM, Mathiesen J, Erler JT, Oddershede LB. Dynamics of cancerous tissue correlates with invasiveness. Sci Rep. 2017;7:43800.
- Elyas E, Papaevangelou E, Alles EJ, Erler JT, Cox TR, Robinson SP, Bamber JC. Correlation of ultrasound shear wave elastography with pathological analysis in a xenografic tumour model. Sci Rep. 2017;7(1):165.
- Elyas E, Grimwood A, Erler JT, Robinson SP, Cox TR, Woods D, Clowes P, De Luca R, Marinozzi F, Fromageau J, Bamber JC. Multi-channel optical coherence elastography using relative and absolute shear-wave time of flight. PLoS One. 2017;12(1):e0169664.
- Cox TR, Erler JT, Rumney RMH. Established models and new paradigms for hypoxia-driven cancer-associated bone disease. Calcif Tissue Int. 2017.
- Fingleton B, Lange K, Caldwell B, Bankaitis KV; Board of the Metastasis Research Society. Perspective on the interpretation of research and translation to clinical care with therapy-associated metastatic breast cancer as an example. Clin Exp Metastasis. 2017;34(8):443–447.
2016
- Cox TR, Erler JT. Fibrosis and cancer: partners in crime or opposing forces?. Trends Cancer. 2016.
- Høye AM, Erler JT. Structural ECM components in the premetastatic and metastatic niche. Am J Physiol Cell Physiol. 2016;310(11).
- Cox TR, Gartland A, Erler JT. Lysyl oxidase, a targetable secreted molecule involved in cancer metastasis. Cancer Res. 2016;76(2):188–192.
- Gartland A, Erler JT, Cox TR. The role of lysyl oxidase, the extracellular matrix and the pre-metastatic niche in bone metastasis. J Bone Oncol. 2016;5(3):100–103.
- Liu N, Cox TR, Cui W, Adell G, Holmlund B, Ping J, Jarlsfelt I, Erler JT, Sun XF. Nuclear expression of lysyl oxidase enzyme is an independent prognostic factor in rectal cancer patients. Oncotarget. 2016.
- González-Santamaría J, Villalba M, Busnadiego O, López-Olañeta MM, Sandoval P, Snabel J, López-Cabrera M, Erler JT, Hanemaaijer R, Lara-Pezzi E, Rodríguez-Pascual F. Matrix cross-linking lysyl oxidases are induced in response to myocardial infarction and promote cardiac dysfunction. Cardiovasc Res. 2016;109(1):67–78.
- Nedergaard MK, Michaelsen SR, Perryman L, Erler JT, Poulsen HS, Stockhausen MT, Lassen U, Kjaer A. Comparison of 18F-FET and 18F-FLT small animal PET for the assessment of anti-VEGF treatment response in an orthotopic model of glioblastoma. Nucl Med Biol. 2016;43(3):198–205.
2015
- Creixell P, Schoof EM, Simpson CD, Longden J, Miller CJ, Lou HJ, Perryman L, Cox TR, Zivanovic N, Palmeri A, Wesolowska-Andersen A, Helmer-Citterich M, Ferkinghoff-Borg J, Itamochi H, Bodenmiller B, Erler JT, Turk BE, Linding R. Kinome-wide decoding of network attacking mutations rewiring cancer. Cell. 2015;163(1):202–217.
- Madsen CD, Pedersen JT, Venning FA, Singh LB, Moeendarbary E, Charras G, Cox TR, Sahai E, Erler JT. Hypoxia and loss of PHD2 inactivate stromal fibroblasts to decrease tumour stiffness and metastasis. EMBO Rep. 2015;16(10):1394–1408.
- Madsen CD, Hooper S, Tozluoglu M, Bruckbauer A, Fletcher G, Erler JT, Bates PA, Thompson B, Sahai E. STRIPAK components determine mode of cancer cell migration and metastasis. Nat Cell Biol. 2015;17(1):68–80.
- Miller BW, Morton JP, Pinese M, Saturno G, Jamieson NB, McGhee E, Timpson P, Leach J, McGarry L, Shanks E, Bailey P, Chang D, Oien K, Karim S, Au A, Steele C, Carter CR, McKay C, Anderson K, Evans TR, Marais R, Springer C, Biankin A, Erler JT, Sansom OJ. Targeting the LOX/hypoxia axis reverses many of the features that make pancreatic cancer deadly: inhibition of LOX abrogates metastasis and enhances drug efficacy. EMBO Mol Med. 2015;7(8):1063–1076.
- Venning FA, Wullkopf L, Erler JT. Targeting ECM disrupts cancer progression. Front Oncol. 2015;5:224.
- Erler JT. Interdisciplinary research: bold alliances aid translational work. Nature. 2015;517(7535):438.
- Bentires-Alj M, Rajan A, van Harten W, van Luenen HG, Kubicek S, Andersen JB, Saarela J, Cook SJ, Van Minnebruggen G, Roman-Roman S, Maurer C, Erler JT, Bertero MG. Stimulating translational research: several European life science institutions put their heads together. Trends Mol Med. 2015;21(9):525–527.
- Lokody IB, Francis JC, Gardiner JR, Erler JT, Swain A. Pten regulates epithelial cytodifferentiation during prostate development. PLoS One. 2015;10(6):e0129470.
- Cox TR, Schoof EM, Gartland A, Erler JT, Linding R. Dataset for the proteomic inventory and quantitative analysis of the breast cancer hypoxic secretome associated with osteotropism. Data Brief. 2015;5:621–625.
- Rodriguez-Teja M, Gronau JH, Breit C, Zhang Y, Minamidate A, Caley MP, McCarthy A, Cox TR, Erler JT, Gaughan L, Darby S, Robson C, Mauri F, Waxman J, Sturge J. AGE-modified basement membrane cooperates with Endo180 to promote epithelial cell invasiveness and decrease prostate cancer survival. J Pathol. 2015;235(4):581–592.
- Michaelsen SR, Nedergaard MK, Urup T, Villingshoej M, Kjaer A, Perryman L, Erler JT, Lassen U, Poulsen HS. VEGF-C contributes to autocrine VEGFR2 signaling and affects cell viability and tumour growth in glioblastoma. Neuro-Oncology. 2015;17:v41–v44.
2014
- Cox TR, Erler JT. Molecular pathways: connecting fibrosis and solid tumor metastasis. Clin Cancer Res. 2014;20(14):3637–3643.
- Perryman L, Erler JT. Lysyl oxidase in cancer research. Future Oncol. 2014;10(9):1709–1717.
- Perryman L, Erler JT. Brain cancer spreads. Sci Transl Med. 2014;6(247):247fs28.
- Cox TR, Erler JT. Lysyl oxidase in colorectal cancer. Am J Physiol Gastrointest Liver Physiol. 2014;305(10):G659–G666.
- Shen CJ, Sharma A, Vuong DV, Erler JT, Pruschy M, Broggini-Tenzer A. Ionizing radiation induces tumor cell lysyl oxidase secretion. BMC Cancer. 2014;14:532.
- Djidja MC, Chang J, Hadjiprocopis A, Schmich F, Sinclair J, Mršnik M, Schoof EM, Barker HE, Linding R, Jørgensen C, Erler JT. Identification of hypoxia-regulated proteins using MALDI-mass spectrometry imaging combined with quantitative proteomics. J Proteome Res. 2014;13(5):2297–2313.
- Erler JT. Cancer: Disabling defences in the brain. Nature. 2014;508(7494):46–47.
- Cox TR, Erler JT. Fibrosis, cancer and the premetastatic niche. Breast Cancer Manag. 2014;3(6):453–455.
2013
- Chang J, Nicolau MM, Cox TR, Wetterskog D, Martens JW, Barker HE, Erler JT. LOXL2 induces aberrant acinar morphogenesis via ErbB2 signaling. Breast Cancer Res. 2013;15(4):R67.
- Barker HE, Bird D, Lang G, Erler JT. Tumor-secreted LOXL2 activates fibroblasts through FAK signaling. Mol Cancer Res. 2013;11(11):1425–1436.
- Cox TR, Bird D, Baker AM, Barker HE, Ho MW, Lang G, Erler JT. LOX-mediated collagen crosslinking is responsible for fibrosis-enhanced metastasis. Cancer Res. 2013;73(6):1721–1732.
- Mayorca-Guiliani A, Erler JT. The potential for targeting extracellular LOX proteins in human malignancy. Onco Targets Ther. 2013;6:1729–1735.
- Baker AM, Bird D, Welti J, Gourlaouen M, Lang G, Murray G, Reynolds AR, Cox TR, Erler JT. Lysyl oxidase plays a critical role in endothelial cell stimulation to drive tumor angiogenesis. Cancer Res. 2013;73(2):583–594.
- Cox TR, Erler JT. The importance of LOX family members on modulating cell-ECM interactions in carcinogenesis. J Carcinogenesis Mutagenesis. 2013;S13:001.
2012
- Barker HE, Cox TR, Erler JT. The rationale for targeting the LOX family in cancer. Nat Rev Cancer. 2012;12(8):540–552.
- Creixell P, Schoof EM, Erler JT, Linding R. Navigating cancer network attractors for tumor-specific therapy. Nat Biotechnol. 2012;30(9):842–848.
- Baker AM, Lang G, Bird D, Cox TR, Erler JT. Lysyl oxidase enzymatic function increases stiffness to drive colorectal cancer progression through FAK. Oncogene. 2013;32(14):1863–1868.
- Welti JC, Powles T, Foo S, Gourlaouen M, Preece N, Foster J, Frentzas S, Bird D, Sharpe K, van Weverwijk A, Robertson D, Soffe J, Erler JT, Pili R, Springer CJ, Mather SJ, Reynolds AR. Contrasting effects of sunitinib within in vivo models of metastasis. Angiogenesis. 2012;15(4):623–641.
- Erler JT, Linding R. Network medicine strikes a blow against breast cancer. Cell. 2012;149(4):731–733.
- Cox TR, Gartland A, Erler JT. The pre-metastatic niche: is metastasis random?. Bonekey Rep. 2012;1:80.
2011
- Cox TR, Erler JT. Remodeling and homeostasis of the extracellular matrix: implications for fibrotic diseases and cancer. Dis Model Mech. 2011;4(2):165–178.
- Baker AM, Cox TR, Bird D, Lang G, Murray G, Sun XF, Southall S, Wilson J, Erler JT. The role of lysyl oxidase in SRC-dependent proliferation and metastasis of colorectal cancer. J Natl Cancer Inst. 2011;103(5):407–424.
- Barker HE, Chang J, Cox TR, Lang G, Bird D, Nicolau M, Evans HR, Gartland A, Erler JT. LOXL2-mediated matrix remodeling in metastasis and mammary gland involution. Cancer Res. 2011;71(5):1561–1572.
- Barker HE, Erler JT. The potential for LOXL2 as a target for future cancer treatment. Future Oncol. 2011;7(6):707–710.
2010
- Erler JT, Linding R. Network based drugs and biomarkers. J Pathol. 2010;220(2):290–296.
- Graves EE, Vilalta M, Cecic I, Erler JT, Tran PT, Felsher D, Sayles L, Sweet-Cordero A, Le QT, Giaccia AJ. Hypoxia in models of lung cancer: implications for targeted therapeutics. Clin Cancer Res. 2010;16(19):4843–4852.
- Graham HK, Hodson NW, Hoyland JA, Millward-Sadler SJ, Garrod D, Scothern A, Griffiths CE, Watson RE, Cox TR, Erler JT, Trafford AW, Sherratt MJ. Tissue section AFM: in situ ultrastructural imaging of native biomolecules. Matrix Biol. 2010;29(4):254–260.
2009
- Erler JT, Bennewith KL, Cox TR, Lang G, Bird D, Le QT, Koong A, Giaccia AJ. Hypoxia-induced lysyl oxidase is a critical mediator of bone marrow cell recruitment to form the pre-metastatic niche. Cancer Cell. 2009;15(1):35–44.
- Levental KR, Yu H, Kass L, Lakins JN, Egeblad M, Erler JT, Fong SF, Csiszar K, Giaccia A, Weninger W, Yamauchi M, Gasser DL, Weaver VM. Matrix crosslinking forces tumor progression by enhancing integrin signaling. Cell. 2009;139(5):891–906.
- Bennewith KL, Huang X, Ham CM, Graves EE, Erler JT, Kambham N, Feazell J, Yang GP, Koong A, Giaccia AJ. The role of tumor cell-derived connective tissue growth factor (CTGF/CCN2) in pancreatic tumor growth. Cancer Res. 2009;69(3):775–784.
- Le QT, Harris J, Magliocco AM, Kong CS, Diaz R, Shin B, Cao H, Trotti A, Erler JT, Chung CH, Dicker A, Pajak TF, Giaccia AJ, Ang KK. Validation of lysyl oxidase as a prognostic marker for metastasis and survival in head and neck squamous cell carcinoma. J Clin Oncol. 2009;27(26):4281–4286.
- Erler JT, Weaver VM. Three-dimensional context regulation of metastasis. Clin Exp Metastasis. 2009;26(1):35–49.
- Granchi C, Funaioli T, Erler JT, Giaccia AJ, Macchia M, Minutolo F. Bioreductively activated lysyl oxidase inhibitors against hypoxic tumours. ChemMedChem. 2009;4(10):1590–1594.
Invited book chapters
Erler JT, Giaccia AJ. Critical steps in cancer metastasis. Chapter 3 in: Abeloff’s Clinical Oncology. Elsevier, 2008.
El Rayes T, Gao D, Altorki N, Cox TR, Erler JT, Mittal V. Biomarkers of the tumor microenvironment: Basic studies and practical applications. Springer, 2016. ISBN 978-3-319-39145-8.
Chang J, Erler JT. Quantification of lung metastases from in vivo mouse models. In: Tumour Microenvironment and Cellular Stress. Springer, 2015. ISBN 978-3-319-26664-0.
Cox TR, Erler JT. Remodeling of the extracellular matrix. In: Cell and Molecular Biology of Breast Cancer. Humana Press, 2013. ISBN 978-1-62703-633-7.
Chang J, Erler JT. Hypoxia regulated metastasis. In: Tumour Microenvironment and Cellular Stress. Springer, 2013. ISBN 978-1-4614-5914-9.
Rankin EB, Erler JT, Giaccia AJ. Critical steps in cancer metastasis. Chapter 3 in: Abeloff’s Clinical Oncology. Elsevier, 2013.
Bennewith KL, Erler JT, Giaccia AJ. Pre-metastatic niches. Chapter 8 in: Tumour Micro-environment. John Wiley, 2010. ISBN 978-0-4707-4996-8.