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I am a specialist in pathology and cytology since 1976, have worked for several years as a clinical pathologist at the Department of Pathology, Rigshospitalet, and served as professor emeritus at BRIC since 2018. My research is focused on the the field of pathology and cell biology, where I have and still am contributing with DNA sequencing, production of monoclonal and polyclonal antibodies and expression studies of several proteins including laminin, tetranectin, and ADAM12.
Kamilla Westarp Zornhagen
During my PhD I studied the tumour microenvironment and its heterogeneity in spontaneous canine soft tissue sarcomas using different molecular markers. Now my research is focused on the extracellular matrix (ECM) and how it affects metastasis.
The past few years I have worked with exercise oncology in a research environment that combined mechanistic preclinical studies with clinical training interventions studies in cancer patients. My current research focuses on elucidating whether exercise modulates ECM components in the tumor microenvironment to foster anti-cancer conditions and limit metastatic development.
The past few years I have worked with translation reasearch, ADAMs, the tumor microenvironment, organoids, and circulating tumor cells, which will also be my research focus here at BRIC.
I am intrigued by the tumor microenvironment; specifically how cancer cells hijack the vascular system to their benefit. My current research investigates how tumor-driven angiocrine signaling feeds back on the growing tumor to drive loco-vascular invasion and subsequent metastasis.
Kasper J. Mygind
I have worked on protein maturation and transport in cells, more specifically how proteins exit the ER and are transported into the Golgi apparatus. To this end I have worked on small GTPases involved in Golgi integrity. I am currently focused on two research areas, first genome modulation (knock-out and knock-in) to study endogenous gene functions. Here I have developed a library of reporter cells enabling us to study protein function as well as cell-cell interactions in vitro and in vivo. Second research area is understating how soluble Basigin / CD147 are pro-tumorigenic
I want to explore what happens within stromal tissue during metastasis, in particular how the tumour microenvironment promotes cancer progression. My PhD focuses on changes in cell populations during metastatic disease and how stromal cells contribute to changes in the ECM. I will apply single cell RNA sequencing to explore this area.
Joana Leitão Castro
During my PhD, I aim to understand the cellular communication between cancer cells and cancer associated fibroblasts (CAFs), as well as to unravel the molecular mechanism by which cancer cell-derived ADAM12 activates the tumor stroma and promotes ECM production. Overall, my goal is to identify new strategies to limit the desmoplastic response as a way to improve cancer treatments.
I’m a PHD student at BRIC. My research interest is about single-cell RNA-sequencing and machine learning applied on large-scale biological data analysis. Now I’m focusing on spatial transcriptomics.
Freia Isak Jørgensen
I am a molecular biomedicine bachelor student, and will as part of my bachelor thesis help Victor investigates how tumor-driven angiocrine signaling feeds back on the growing tumor to drive loco-vascular invasion and subsequent metastasis.
Alejandro Mayorca Guiliani
Jesper Thorhauge Pedersen
Lukram Babloo Singh
Marc Garcia Montolio
Marina Crespo Bravo
Peter Bavngaard Thrane
Pier Giorgio Amendola
Raphael Reuten (LinkedIn profile)
Sebastian R. Nielsen
Sofie Dahl Tolstrup
Tine Thurison Røndbjerg