The Erler Lab is a cancer biology research group at the Biotechnology Research and Innovation Centre (BRIC) at the University of Copenhagen. We are interested in understanding the underlying processes contributing to tumour progression and patient treatment failure.
All solid tumours over 1cm3 contain regions of hypoxia due to inadequate blood supply from insufficient and disorganised vasculature. Tumour hypoxia is clinically associated with poor patient outcome; and hypoxic tumour cells are highly aggressive, metastatic and resistant to therapy, through relatively undefined mechanisms. Understanding how tumours acquire the ability to invade surrounding tissue and metastasise is critical for the identification of new targets and development of therapies against metastatic disease.
The Erler lab is part of the Biotech Research and Innovation Centre, BRIC at the University of Copenhagen
Key words: Erler, cancer, cancer research, metastasis, tumour, tumor, hypoxia, LOX, Lysyl oxidase, BRIC, Copenhagen, København